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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Nai-Hong Chen

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2 papers indexed here

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Aug 2026

A Biomimetic Nanoplatform Alleviates Depression via GRP75-Targeted Mitochondria-Associated Endoplasmic Reticulum Membranes Disassembly and Nanozyme-Driven ROS Scavenging.

In mice subjected to chronic social defeat stress (CSDS), P/F-Rg1@M effectively alleviated depressive-like behaviors, including social avoidance and anhedonia, and provides a nanotherapeutic approach that integrates structural organelle remodeling with microenvironmental regulation for psychiatric disorders.

Wen-Fei Wang, Pengxiang Zhang, Ye Peng et al. · 0 citations
Sep 2026

Notoginsenoside R1 attenuates post-ischemic pyroptosis: a novel CKLF1-endoplasmic reticulum stress pathway-mediated mechanism.

BACKGROUND Ischemic stroke induces neuronal pyroptosis driven by excessive endoplasmic reticulum (ER) stress, which exacerbates secondary brain injury. Notoginsenoside R1 (NGR1) has demonstrated neuroprotective properties; however, whether its mechanism involves the modulation of chemokine-like factor 1 (CKLF1)-mediate...

Han-Long Wang, Yang Sun, Sha-Sha Liu et al. · 0 citations

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