Ziyuglycoside I Attenuates Deinagkistrodon acutus Venom-Induced Injury in Renal Tubular Epithelial Cells by Modulating PAR1-NLRP3-IL-1β Signaling.
INTRODUCTION Sanguisorba officinalis L. (Di Yu) has traditionally been used for snakebite treatment. Ziyuglycoside I, a major bioactive constituent of Di Yu, exhibits anti-inflammatory activity, but its role in snake venom-associated renal injury remains unclear. This study aimed to investigate its potential protective...