Open access
Jul 2026
STRUMP-I: Structure-Based Machine Learning Approach to pMHC-I Binding Prediction Using Force Field Energy Features
STRUMP-I (STRUcture-based pMHC Prediction for class I), a novel pMHC-I binding prediction tool that directly leverages a broad set of force-field-derived energy terms as machine learning features, achieved performance comparable to state-of-the-art sequence-based models overall and showed a clear advantage for alleles...
Adam Voshall, Jeongjun Chae, Honglan Li et al.
· Computational and Structural... · 0 citations