Bile acids, as cholesterol metabolites, orchestrate a regulatory network with mitochondrial quality control (MQC) through nuclear receptor FXR, membrane receptor TGR5, and other signaling molecules, modulating mitochondrial biogenesis, dynamic equilibrium, selective autophagy, and redox homeostasis. TGR5 promotes PGC-1...
Xue-Ru Jia, Ze-Han Zhang, Xiao-Yu Lin et al.· Pharmacological Research· 0 citations
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