Author

Nan Wu

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Open access Oct 2026

Hypoglycemic Agent Targets and Susceptibility to Lower Respiratory Infection: A Pharmacogenomic Mendelian Randomization Study

Background/Objectives: Patients with type 2 diabetes face heightened risks of lower respiratory tract infections, but whether distinct glucose-lowering drug targets differentially alter pulmonary susceptibility remains unclear. We investigated how genetically proxied perturbations of major antidiabetic targets relate t...

Tai-Kang Yao, Nan Wu, Yan-Qiu Ma et al. · Genes · 0 citations

Open access Aug 2026

A lifestyle-driven inflammatory load index and its circulating metabolomic signature identify susceptibility to hospital-recorded acute respiratory infections: a population-based cohort study of 295,679 adults

In a population-scale cohort, a lifestyle-anchored inflammatory load index showed a graded association with hospital-recorded ARIs, and a circulating NMR-derived MRS, dominated by fatty-acid-related biomarkers and including the established low-grade-inflammation marker glycoprotein acetylation (GlycA), accounted for ap...

Xu-Feng Fu, Xiao-Hua Li, Xin-Qian Ma et al. · Frontiers in Endocrinology · 0 citations