Myocardial ischemia/reperfusion (I/R) injury impairs the prognosis of patients with cardiovascular disease. Reperfusion induces cardiomyocyte apoptosis and dysregulates autophagy, thereby disrupting cellular homeostasis and exacerbating myocardial injury. Bisdemethoxycurcumin (BDMC), a major active component of Curcuma...
Li-Min Liu, Na-Na Chen, Xin-Ping He et al.· European Journal of Pharmaco...· 0 citations
Ischemic stroke disrupts cerebral metabolism and initiates a cascade of pathological events, including excitotoxicity, mitochondrial dysfunction, and neuroinflammation. These interconnected processes drive neuronal apoptosis, necrosis, and synaptic loss, ultimately leading to irreversible brain injury, persistent neuro...
Jun Tan, He Li, Ming-Hao Song et al.· Journal of Integrative Neuro...· 0 citations
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