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Nandu C. Karingari

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Open access Aug 2026

Smad4 and Eomes converge on a shared transcriptional program associated with inflammatory CD8 T-cell differentiation

The ability of CD8 T cells to mediate protective immunity while limiting immunopathology depends on critical transcription factors such as Smad4 and Eomes that regulate differentiation of activated CTLs. Disruption of transcriptional programs mediated by Eomes and Smad4 in activated CTLs has been implicated in viral in...

Karthik Chandiran, Nandu C. Karingari, Srineeharika Sirigineedi et al. · 0 citations

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