Association of CTLA-4 Gene Polymorphisms and Serum Soluble CTLA-4 Levels with Psoriasis Vulgaris
Objective: Psoriasis vulgaris (Pv) is a chronic inflammatory condition with a genetic and immunological basis. Cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) is a key immunoregulatory molecule expressed on T cells that transmits inhibitory signals important for maintaining immune homeostasis. Single nucleotide po...