Author

Nantawat Satthawiwat

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Open access Sep 2026

Zfp469 Deletion Attenuates Liver Fibrosis by Suppressing Extracellular Matrix Production in Hepatic Stellate Cells.

BACKGROUND Liver fibrosis is driven by excessive extracellular matrix (ECM) deposition following chronic injury. Mutations in the human zinc finger protein 469 (ZNF469) cause Brittle Cornea Syndrome, a systemic connective tissue disorder, yet its functional role in hepatic fibrogenesis remains unexplored in vivo. This...

Nantawat Satthawiwat, Archittapon Nokkeaw, Bootsakorn Boonkaew et al. · Biomedical Journal · 0 citations

Gut microbiota and genetic polymorphisms correlated with liver fibrosis in metabolic dysfunction-associated steatotic liver disease

Metabolic dysfunction-associated steatotic liver disease (MASLD) is a common chronic liver disorder associated with obesity, type 2 diabetes, and hyperlipidemia. Steatosis leads to fibrosis, cirrhosis, and hepatocellular carcinoma. Gut microbiota and host genetics contribute significantly, while the role of the gut myc...

Nantawat Satthawiwat · 0 citations