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Author

Naoko Abe

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Open access Sep 2026

Enhanced CRISPR-Cas3-mediated genome editing using circularized crRNAs

Summary Type I-E CRISPR-Cas3 represents a genome-editing technology in which large deletions averaging several kilobases are introduced in target regions. However, its genome-editing efficiency varies considerably across targets and cell types, making it difficult to achieve consistent results. Here, we investigated th...

Kouya Mikamo, K. Yoshimi, Naoko Abe et al. · 0 citations

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