Studying synergistic effects of temozolomide and vistusertib in glioblastoma cells
Targeting the mTORC2/AKT/BABAM1 axis with vistusertib worked synergistically with TMZ in GBM by impairing the BRCA1-A complex and HR repair and sustained tumour suppression in both 2D and 3D models.
Napatsakon Youngsanbhu
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