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Open access Sep 2026

Bioanalytical Method Development and Validation for a Novel Secretory Phospholipase A₂ Inhibitor by LC-MS/MS and its Application to a Pharmacokinetic Study in Mice

Objective: This study aimed to develop and validate a sensitive LC–MS/MS method for quantifying a novel Secretory phospholipase A₂ (sPLA₂) inhibitor, compound-7(L), in mouse plasma and to evaluate its application in pharmacokinetic studies. Methods: A bioanalytical LC–MS/MS method was developed and validated according...

Nageswararao Pulakundam, Bhavesh D. Patel, Naresh P. et al. · 0 citations

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