Open access
Aug 2026
PARP inhibition enhances the antitumor activity of HER3-DXd in non-small cell lung cancer
It is suggested that combining HER3-DXd with PARP inhibitors with a significant synergy is observed with PARP inhibitors, effective in both EGFR- and KRAS-mutated NSCLC models, effectively targeting diverse NSCLC subtypes.
Linh Lin, Narges Moradi, I. Lähdeniemi et al.
· Cell Reports Medicine · 0 citations