Author

Narumi Yoshihara

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Open access Jul 2026

Adenosine 5'-monophosphate prevents sepsis-associated muscle wasting by activating AMPK and suppressing IL-1β inflammatory cytokines

It is demonstrated that AMP effectively mitigates SAMW by activating AMPK and suppressing IL-1β-mediated molecular pathways and highlighting the potential of AMP as a novel therapeutic agent for preserving skeletal muscle functionality and morphology in sepsis.

I. Yoshihara, Narumi Yoshihara, K. Hanafusa et al. · Journal of Intensive Care · 0 citations