Natalie Z. McLean

α-Synuclein pathology differentially alters T-type calcium currents in vulnerable and resilient substantia nigra dopaminergic subpopulations

Aggregation of α-synuclein protein is a characteristic of Parkinson’s disease pathology that relates to the degeneration of vulnerable dopaminergic neurons and motor symptoms of the disease. However, α-synuclein pathology can contribute to neuronal dysfunction by disrupting several processes within the cell, including...