The Olfr519/OR10A3 signaling Amplifies Macrophage Inflammasome Activation and Drives Atherosclerosis 2260066
Olfactory receptors (ORs), the largest family of G protein—coupled receptors, are emerging regulators of innate immunity. While specific ORs, such as Olfr2, have been linked to vascular inflammation, the broader role of OR signaling in macrophage-driven atherogenesis remains unclear. Aortic macrophages fro...