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Author

Natasha Pillay-Smiley

2 papers indexed here

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Open access Oct 2026

Longitudinal Caregiver- and Patient-reported Health-related Outcomes of Pediatric Patients with High-grade Gliomas Enrolled on CONNECT1701 and CONNECT1702

Children with HGG, including DIPG, experience psychosocial and physical sequelae, negatively impacting health-related quality of life (HRQoL). Limited data exists on psychosocial functioning in this population. We longitudinally assessed caregiver-proxy and patient-reported HRQoL and functional outcomes of childr...

Mariah L. Wright-Nadkarni, Emily L. Moscato, Joseph R. Stanek et al. · 0 citations
Aug 2026

A CAR-T Tonic Signaling Code Predicts Anti-Tumor Efficacy in Diffuse Midline Glioma.

BACKGROUND Diffuse middle glioma (DMG or DIPG) is a fatal pediatric brain tumor. Although chimeric antigen receptor (CAR) T-cell therapy shows promise, clinical outcomes remain inconsistent due to premature exhaustion, underscoring a critical need to improve CAR-T persistence. A major barrier to CAR-T efficacy is antig...

Bing Deng, Xiaowen Zhong, Da-Zhuan Xin et al. · 0 citations

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