Author

Nathan A. Gillespie

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Open access Oct 2026

Association between polygenic liability to depression and lifetime depression in at-risk adolescents.

Internalising symptoms including depression, anxiety and somatic symptoms in adolescence are common. They can be transient, but they can also persist and progress to major depressive disorder (MDD) Polygenic risk scores for major depression (MD-PGS) may help identify which symptomatic adolescents are at greatest risk o...

E. Byrne, Nathan A. Gillespie, J. Najman et al. · Molecular Psychiatry · 0 citations

Open access Sep 2026

The Changing Landscape of Genetic Risk: Age-Related Effects of Polygenic Scores for Suicidal Behaviors

Suicidal thoughts and behaviors are a persistent public health challenge. Twin studies and genome-wide association studies (GWAS) have revealed moderate genetic influences. In exploratory analyses, we evaluated whether the impact of polygenic risk scores (PRSs) for suicide ideation (SI-PRS) and attempt (SA-PRS) varied...

Nathan A. Gillespie, Séverine Lannoy, Mallory Stephenson et al. · Research Square · 0 citations