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Nathan Hays

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Open access Jul 2026

Ligand-Specified Signaling Efficacy Defined by Unique Transitions in G Protein Conformations

This research established a 3-state model of Gαs conformational landscape and quantitatively investigated the conformational transitions and dynamics of Gαs proteins in response to different ligand-bound receptors, enabling a novel GPCR model that integrates quantitative G protein conformational dynamics at the atomic...

Xu-Dong Wang, Wen-Kai Sun, Nathan Hays et al. · 0 citations

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