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Author

Nathaniel Foley

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2 papers indexed here

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Open access Oct 2026

Photoreceptor replacement therapy using a tissue scaffold shows evidence of donor-host integration in non-human primate retina.

Retinal degeneration is characterized by progressive photoreceptor (PR) loss, leading to visual impairment and ultimately blindness. PR replacement is a promising therapeutic strategy, but surgical delivery remains challenging, and efficacy in primates remains unknown. Tissue scaffolds hold potential for better control...

Laura Patak, Soumaya Belhadj, Agustín Luz-Madrigal et al. · 0 citations
Aug 2026

A 3D human retina model reveals a non-cell-autonomous and non-neuronal mechanism of photoreceptor loss in a lysosomal storage disorder.

Treatment with recombinant human acid ceramidase (rhAC) ameliorated photoreceptor degeneration in both the CLN3 disease RO-RPE model and CLN3 miniswine eyes, suggesting that rhAC could be a therapeutic approach for retinal degeneration in CLN3 disease.

Jimin Han, Nathaniel Foley, Sonal Dalvi et al. · 0 citations

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