A Quantitative Assessment of MRI-Visible Perivascular-Space Burden Across the Cognitive Spectrum: Associations with APOE ε4 Status and Venous Sinus Volume
Background/Objectives: Perivascular spaces (PVS) are MRI-visible compartments surrounding cerebral vessels and are increasingly interpreted as markers of cerebral small-vessel disease and glymphatic-system dysfunction. PVS burden is multifactorial, with possible contributions from vascular risk, atrophy, white matter d...