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Navyaka Padavala

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Open access Aug 2026

Evolutionary divergence V-ATPase function in macropinocytic cup remodeling

This work uncovered an unprecedented role of V-ATPase in shaping the macropinocytic cup in the pathogenic amoeba Entamoeba histolytica and highlights the novel role of V-ATPase in directly driving actin polymerization, in conjunction with phosphatidic acid, to shape the macropinocytic cup.

Bhagyashree Chordiya, Navyaka Padavala, Amisha Sharma et al. · 0 citations