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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Nayan Kumar Mahadeva

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Review Sep 2026

PDK1 signaling in cancer: Current status and future perspectives.

Experimental results from breast, lung, gastric, liver, hematological, and melanoma models suggest that dysregulated PDK1 signaling can increase the output of the PI3K-AKT-mTOR pathway, invasion, metabolic adaptation, and resistance to specific hormonal, chemotherapeutic, and targeted therapies.

Darshana Ballagere Honnasiddappa, M. Ramar, Tincy Biju et al. · 0 citations

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