Author

Nayuta Yakushiji-Kaminatsui

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Open access Sep 2026

Molecular analysis of Aldh1a2 conditional inactivation in developing limbs reveals mechanisms of retinoic-acid mediated interdigital apoptosis

Introduction Retinoic acid (RA) plays a plethora of functions during embryonic development as well as post-natal life. In particular, RA function during limb development is associated with interdigital cell death. However, the molecular mechanism(s) through which RA signaling contributes to interdigital cell death rema...

Rodrigue Peraldi, Yacine Kherdjemil, Gabriel Villiard et al. · Frontiers in Cell and Develo... · 0 citations

Open access Aug 2026

SPIN1 selectively silences evolutionarily young transposable elements through chromatin regulation

SPIN1 uses a histone-state-based mechanism to identify and repress young TEs in pluripotent cells, mechanistically distinct from its germline mode in which SPIN1 cooperates with the PIWI–piRNA pathway to promote DNA methylation, illustrating how a single histone reader engages distinct silencing machineries across cell...

Hiromi Yamada, Chikara Takeuchi, Clive S. Barker et al. · bioRxiv · 0 citations

Open access Jul 2026

Extending the residence period of allogeneic iPSC-derived invariant natural killer T cells in humanized mice by editing HLA class I expression

An approach to extend the residence time of iPSC-derived invariant natural killer T (iPSC-derived iNKT) cells in humanized mice by genetically modifying HLA class I expression is presented, with the potential to develop universal off-the-shelf immunotherapy.

Yun‐Hsuan Chang, T. Aoki, M. Okoshi et al. · Frontiers in Cell and Develo... · 0 citations