Open access
Sep 2026
Targeting α6β1 Integrin Signaling with Pranlukast to Modulate Venous Endothelium Function and Reduce Post-Thrombotic Vein Wall Injury.
BACKGROUND Post-thrombotic syndrome (PTS) develops in 20-50% of patients following deep vein thrombosis (DVT) due to persistent vein wall injury, inflammation, and fibrotic remodeling. Current anticoagulant therapies do not directly address PTS pathogenesis and carry bleeding risks. We characterized the extracellular m...
Alessia Taylor, Oscar Moreno, Catherine E. Luke Lvt et al.
· Journal of Vascular Surgery:... · 0 citations