PURPOSE
Zonisamide, an anticonvulsant with GABAergic and glutamatergic effects, has been investigated as a treatment for alcohol use disorder (AUD), but its efficacy and tolerability remain uncertain. This systematic review and meta-analysis synthesizes evidence from randomized controlled trials evaluating zonisamide f...
Vivien Obitulata, Kush Sehgal, Juan Diego Freire Florez et al.· Journal of Clinical Psychoph...· 0 citations
BACKGROUND AND AIMS
Persistent IBS-like symptoms affect up to one-third of patients with inflammatory bowel disease (IBD) in remission, representing a major unmet need not addressed by anti-inflammatory therapies. Despite increasing use of dietary and gut-brain-targeted strategies, their efficacy in this population rem...
M. Goyal, Allen A. Lee, Dhruvi Shah et al.· Clinical Gastroenterology an...· 0 citations
Chronic ocular surface pain (COSP) is a debilitating condition of the eye driven by nociceptive, nociplastic, and neuropathic mechanisms. While individual studies using functional neuroimaging techniques to investigate ocular pain exist, the full extent, methodologies, and cumulative findings of this body of literature...
Eliot N. Haddad, Radhika S. Amin, Neil Nero et al.· Survey of ophthalmology· 0 citations
Digital health–supported interventions for secondary stroke prevention seem feasible and acceptable, with evidence of modest short-term improvements in blood pressure, but clinical effectiveness across other vascular risk factors remains inconsistent.
Shervin Badihian, Margarita Fedorova, Bradley Ong et al.· Neurology Clinical Practice· 0 citations
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