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Nerissa T. Viola

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Open access Aug 2026

scFv-Fcs as a Radiotheranostic Platform for Targeting TRA-1–60 in Pancreatic Cancers

Purpose TRA-1–60 (TRA) is an established cancer stemness marker implicated in tumor initiation, therapeutic resistance, and disease relapse. It is minimally expressed in normal differentiated tissues, making it an appealing biomarker for immunopositron emission tomography (immunoPET) imaging and radiopharmaceutical the...

Nerissa T. Viola · 0 citations
Open access Aug 2026

scFv-Fcs as a Radiotheranostic Platform for Targeting TRA-1-60 in Pancreatic Cancers

A smaller TRA-targeted scFv-Fc antibody fragment was developed and evaluated as a unified immuno-theranostic platform for both noninvasive molecular imaging and targeted RPT of TRA+ tumor subpopulations and established a TRA-targeted radiotheranostic platform which integrated immunoPET imaging and targeted RPT of TRA+...

Sajmina Khatun, Farzaneh Rezazadeh, A. Deck et al. · 0 citations

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