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Niccolò Orlandi

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Open access Oct 2026

Dual Antiglutamate Therapy in Super-Refractory Status Epilepticus After Cardiac Arrest (SUPER-CAT Study)

Background and Objectives The SUPER-refractory status epilepticus (SE) after Cardiac Arrest Treatment (SUPER-CAT) study evaluated the efficacy and safety of dual antiglutamate therapy (combined AMPA and NMDA receptor blockade) in patients with super-refractory SE (SRSE) after cardiac arrest and without unfavorable prog...

Simone Beretta, Matteo Pozzi, Simone Tagliabue et al. · 0 citations
Open access Sep 2026

Statin use and risk of remote seizure after first new onset status epilepticus.

OBJECTIVE Preclinical evidence supports the role of statins as antiepileptogenic agents. In this study, we investigated the risk of remote unprovoked seizures (RS) according to the use of statin therapy in a cohort of first-ever status epilepticus (SE) survivors. METHODS Retrospective analysis was made of adult patie...

Niccolò Orlandi, G. Giovannini, Lisa Taruffi et al. · 0 citations
Review Open access Aug 2026

Claustrum Involvement in New Onset Refractory Status Epilepticus: A Systematic Review

The claustrum sign is a distinctive neuroimaging finding characterized by bilateral T2/FLAIR hyperintensity of the claustrum, one of the most interconnected regions of the human brain, which may support early diagnosis and targeted treatment.

Margherita Burani, L. Muccioli, G. Giovannini et al. · 0 citations
Open access Aug 2026

Status epilepticus in adults: From etiology to treatment response.

Heterogeneity exists within the spectrum of acute symptomatic causes; distinct etiological subcategories may carry different risks of refractoriness and superrefractoriness.

Simona Lattanzi, G. Giovannini, Niccolò Orlandi et al. · 2 citations · ⚡1
Open access Aug 2026

Cognitive and Biomarker Signatures of Late-Onset Temporal Lobe Epilepsy

Cognitive and CSF phenotype of LO-TLE with normal CSF AD biomarkers is characterized by distinct cognitive and biological features compared with MCI-AD, suggesting a disease process independent of AD.

Alessia Casarini, Alice Ballerini, Riccardo Maramotti et al. · 0 citations
Open access Jul 2026

A Predictive Model for Short-Term Mortality After Status Epilepticus

The ACARD score is a user-friendly tool developed to predict 30-day mortality after nonhypoxic SE and has the potential to identify participants at high risk of short-term mortality and outperform the performance of other available scoring systems.

Simona Lattanzi, E. Trinka, P. Bosque-Varela et al. · 0 citations

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