Open access
Aug 2026
Rho/ROCK-dependent actomyosin contractility drives extracellular vesicle release from the cilium
It is demonstrated that the release of extracellular vesicles from the cilium relies on actomyosin contractility supported by non-muscle myosin IIA acting downstream of the RhoA-ROCK signaling pathway, and that the cilia of these cells release EVs independently of de novo actin polymerization.
William J. Spencer, Margaux J. Kreitman, Nicholas F. Schneider et al.
· bioRxiv · 0 citations