Author

Nicolas Gilbert

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Open access Aug 2026

Preventive Treatment With Ceftriaxone Attenuates Neuropathic Pain and Anxiety-Like Behaviour in a Mouse Model of Partial Sciatic Nerve Ligation.

BACKGROUND Neuropathic pain is associated with anxiety-like disorders, suggesting shared neurobiological mechanisms. Glutamatergic dysregulation and impaired astrocytic glutamate uptake, particularly via the astrocytic transporter GLT-1, have been implicated in central sensitization and associated affective disorders....

Pauline Braconnier, Mathilde Charlier, Alessia Romanin et al. · European Journal of Pain · 0 citations

Review Open access Sep 2026

K2P channels as emerging therapeutic targets for pain: insights from functional studies and transcriptomic analyses

An integrated overview of K2P channel function in pain is provided, combining data from anatomical, transcriptomic, electrophysiological, genetic, behavioral, and pharmacological studies to position K2P channels as a versatile family of targets for precision analgesia and future multimodal treatments aimed at restoring...

Nicolas Gilbert, Kelly Jeanne, A. Li et al. · Frontiers in Pharmacology · 0 citations