Open access
Aug 2026
Expression of the C-type lectin receptor CD205 on B cells mediates HIV-1 binding and trans infection of CD4+ T cells
Antigen presenting cells (APC) can bind HIV-1 and subsequently trans infect CD4+ T cells. In comparison to direct (cis) infection of CD4+ T cells by free virus, APC-mediated HIV-1 trans infection is significantly more efficient and requires lower virus titers. As such, B cell-mediated HIV-1 trans infection of CD4+ T ce...
A. Gerberick, Allison E. DePuyt, Peter E. J. Shoucair et al.
· bioRxiv · 0 citations