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Nicole A. Chittim

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Open access Oct 2026

PIEZO1 Is a Contextual Mechanosensor and Its Depletion in Scx‐Lineage Cells Accelerates Structural and Functional Recovery

Findings reveal a context‐dependent role for PIEZO1 in tendon biology: while PIEZO1 supports mechanosensing and adaptation in mature tendon, it enables wound‐site recruitment of Scx+ fibroblast populations that impair healing after injury.

Nicole A. Chittim, M. Wolleb, M. Greenwald et al. · 0 citations

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