The P2X7R-NLRP3 inflammasome axis in Alzheimer’s disease and therapeutic potential of synthetic and plant-derived natural compounds: A review
This review summarizes the progressive molecular events linking Αβ and tau pathology to neuroinflammation via the P2X7R-NLRP3 inflammasome axis, while underscoring the therapeutic potential of plant-derived bioactive compounds as well as synthetic molecules in mitigating the progression of Alzheimer’s disease.