Characterization of Perineural Invasion Parameters for Risk Stratification in Oral Squamous Cell Carcinoma.
BACKGROUND Perineural invasion (PNI) is an established adverse prognostic factor in oral squamous cell carcinoma (OSCC), but the implications of its extent as well as its relationship with surgical margin status and the extent of microscopic tumor spread remain unclear. METHODS We retrospectively analyzed 165 patient...