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Nikhil C. Mathur

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Open access Oct 2026

A humanized eNAMPT -neutralizing monoclonal antibody reduces cancer-induced bone pain and osteoclastogenesis in murine breast cancer model

Cancer-induced bone pain (CIBP) is a common symptom among patients with metastasized cancer, however, health professionals often face challenges in managing patients’ pain. Extracellular nicotinamide phosphoribosyltransferase (eNAMPT) is a DAMP overexpressed in metastatic breast carcinoma that binds to Toll-Like...

Nikhil C. Mathur, Ethan Villaroel, Isabel Villaroel et al. · 0 citations

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