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Author

Niklas Amann

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Open access Oct 2026

Moderate-risk variants in hereditary breast and ovarian cancer: seven-year experience from a specialized center

Moderate-risk gene variants represent an increasingly recognized component of hereditary breast and ovarian cancer (HBOC) predisposition, yet their clinical interpretation and management remain less standardized than those of high-penetrance genes. This study provides a seven-year real-world evaluation of genetic varia...

A. Krückel, Matthias W. Beckmann, L. Brückner et al. · 0 citations
Open access Jul 2026

AI-enabled clinical decision support in breast cancer care: a blinded multicenter benchmarking study comparing medically specialized with a general-purpose system

The results indicate that while regulatory clearance and domain specialization address key requirements for AI-enabled clinical decision support systems, these factors alone do not translate into superior performance in breast cancer care.

Jonas Freudenberg, J. Knitza, N. Gremke et al. · 0 citations

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