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Author

Nikola G. Malinov

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Open access Sep 2026

A kinetically constrained dynamic flux balance analysis model predicts diverse CHO-cell culture process modes and conditions.

Bioreactor process conditions have a significant effect on Chinese Hamster Ovary (CHO) cell metabolism. However, there exists very limited literature on incorporating process conditions in mathematical models of CHO cell metabolism. To address this limitation, guided by recently published experimental data, we have cur...

J. Reddy, Nikola G. Malinov, Jason Souvaliotis et al. · 0 citations

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