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Niloofar Yousefi

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Preprint Jul 2026

Pre-Registered External Evaluation Yields a Consistent Partial-Replication Category across Three Transcriptomic Foundation Models

A pre-registered, final-test-once evaluation framework that locks the outcome rule, seeds, and target-gene-grouped splits before any test data are seen, and scores each frozen representation against a strong expression baseline, a matched-capacity Gaussian control, and a within-split row-identity (shuffle) control.

Mehrdad Shoeibi, Niloofar Yousefi · 0 citations