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Author

Nimesh D. Desai

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Review Open access Sep 2026

Thoracic aortic disease: prognostic role of gene variants and polygenic risk scores.

BACKGROUND AND AIMS Thoracic aortic aneurysm and dissection (TAAD) can have catastrophic health consequences. Eleven genes have strong or definitive evidence for causing heritable TAAD (HTAAD). The aim of this work was to determine the prevalence and effect of rare, pathogenic or likely pathogenic (P/LP) variants in HT...

J. DePaolo, D. Smelser, Dong-Chuan Guo et al. · 0 citations

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