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Open access Oct 2026

From social isolation to frailty: the chain mediating roles of depression and cognitive decline among Chinese older adults.

BACKGROUND As global aging accelerates, frailty has emerged as a critical public health challenge. Although social isolation is recognized as a prevalent psychosocial risk factor among older adults, the longitudinal mechanisms linking it to frailty-specifically via the chain mediating pathways of depression and cogniti...

Hu-Jiang Yang, Chun-Duo Liang, Jun-Qian Ma et al. · 0 citations

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