Open access
Oct 2026
The Impact of Dietary Fiber Supplementation on Gut-Brain Axis Biomarkers and Symptoms in Functional Constipation: A Meta-Analysis of Randomized Controlled Trials.
BACKGROUND AIMS Dietary fiber is first-line for functional constipation (FC), but its mechanism remains unclear. Emerging evidence suggests gut-brain axis modulation. We conducted a meta-analysis of randomized controlled trials (RCTs) to evaluate fiber's clinical efficacy and its effects on gut-brain axis biomarkers in...
Yue Wang, Qiao-Ying Yan, Fang-Fang Liu et al.
· Clinical and Translational G... · 0 citations