Background Inflammatory bowel disease (IBD) remains difficult to manage in a substantial proportion of patients because conventional systemic therapies may fail to achieve sufficient drug accumulation at inflamed intestinal sites while causing systemic adverse effects. Therefore, localized delivery systems capable of p...
Long-Bin Huang, Chen Kong, Mei-Feng Yang et al.· Journal of Inflammation Rese...· 0 citations
Abstract Gastrointestinal (GI) diseases are increasing in prevalence worldwide and represent a major public health burden. However, current treatments remain limited and are often associated with adverse effects, highlighting the need for innovative therapeutic strategies. Human umbilical cord mesenchymal stem cells (h...
Zhi-Liang Mai, Ning-Ning Yue, Hai-Lan Zhao et al.· International Journal of Nan...· 0 citations
Given its expression pattern, along with its swift internalization and limited expression in most normal tissues, CD74 emerges as a promising target for a wide array of therapeutic approaches like antibody-drug conjugates (ADCs), bispecific antibodies, and Chimeric Antigen Receptor T-cell (CAR-T) therapy.
Shuni Zhang, Shuzhen Xiong, Jiajia Cao et al.· Leukemia and Lymphoma· 0 citations
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