Tetrasubstituted Chiral Calix[4]arene Platform for Tunable Chiroptical Detection of d / l -Amino Acids
Detection of amino acid chirality is important for biomedical applications, yet the direct recognition of underivatized d/l-amino acids remains challenging because of their subtle stereochemical differences. Herein, we report a pair of upper-rim tetrasubstituted chiral Schiff-base calix[4]arenes, R-C4A and S-C4A, in...