CPS1 promotes colorectal cancer progression by inducing EMT and activating TGF-β/Smad signaling pathway
Summary Colorectal cancer (CRC) is a highly lethal digestive malignancy, particularly in metastatic cases. Carbamoyl-phosphate synthase 1 (CPS1), a key mitochondrial enzyme involved in the urea cycle, has been implicated in multiple cancers. However, its role in CRC remains poorly understood. This study demonstrated th...