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Open access Sep 2026

Causal effects of gut microbiota on functional gastrointestinal disorders: a bidirectional Mendelian randomization study

Genetically predicted IBS risk was associated with lower abundances of Turicibacter and Slackia, whereas no robust reverse associations were observed for FD, and several microbial taxa are identified as candidates for further mechanistic and clinical validation rather than established risk factors or therapeutic target...

Yu-Tong Cheng, Qiu-Ai Shu, Zi-Wei Wang et al. · 0 citations
Preprint Sep 2026

Operationalizing open-ended biological discovery across single-cell representations

PROSPECTor is developed, an end-to-end framework that searches for reproducible biological structures across conventional expression representations and diverse foundation-model embeddings, translating robust signals into quantitatively testable candidate hypotheses.

Ning Zhang, Zi-wei Wang, Ning Xie et al. · 0 citations

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