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Ning-Yu Ding

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Open access Oct 2026

Generation of a human induced pluripotent stem cell line (ZZUNEUi040-A) from a male patient with hypertrophic cardiomyopathy carrying a heterozygous TPM1 (c.644C > T) mutation.

Tropomyosin 1 (TPM1) encodes tropomyosin alpha-1 chain, a key cardiac sarcomere component, while TPM1 mutations cause hypertrophic cardiomyopathy (HCM), a major cause of sudden cardiac death in the young. We generated the human iPSC line ZZUNEUi040-A from peripheral blood mononuclear cells of a 10-year-old male with no...

Jian-Chao Zhang, Ren-Cai Peng, Ning-Yu Ding et al. · 0 citations

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