Sep 2026
Design, synthesis and anti-inflammatory evaluation of arylamide-modified pyrrolo[2,3-d]pyrimidine derivatives against acute lung injury.
Treatment with compound B19 significantly alleviated pulmonary inflammation and edema, attenuated inflammatory cell infiltration, and markedly decreased pro-inflammatory cytokine levels in bronchoalveolar lavage fluid and provides a solid foundation for the further development of pyrrolo[2,3-d]pyrimidine-based anti-inf...
Chun-Wei Shen, Ren-Ying Wang, Bin Liu et al.
· Bioorganic chemistry (Print) · 0 citations