Author

Ning Zhang

3 papers indexed here

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Open access Aug 2026

Multi-functional bionic nanoparticles for precise neuronal targeting and synergistic therapy in Alzheimer's disease

Alzheimer's disease (AD) is characterized by core pathological mechanisms including amyloid-β plaque aggregation, cholinergic dysfunction, and neuronal apoptosis. Given the complex interplay of these pathways, combination therapies are emerging as more effective strategies than single-target approaches. The success of...

Yue Na, C. Liu, Xinming Bi et al. · Materials Today Bio · 0 citations

Review Open access Jul 2026

Plant Polysaccharides in Alzheimer’s Disease: From Phytochemistry to Microbiota-Gut–Brain Axis Mechanisms—Resolving the Pharmacokinetic-Pharmacodynamic Paradox

A theoretical framework for TCM polysaccharide intervention in AD via the gut–brain axis is provided and a pharmacological basis for developing natural product-based AD therapies is provided.

Jie Gao, Liheng Li, Qi Liu et al. · Molecules · 0 citations

Review Jul 2026

Microneedle-mediated drug delivery systems for brain diseases.

This work overviews preclinical microneedle formulations and key signaling pathways, and establishes a matching framework linking therapeutic targets, drugs, and microneedle types that may guide the rational design and clinical translation of microneedle-mediated brain-targeted drug delivery systems.

Jia Li, Yu-Bo Wang, Xin Ma et al. · Nanomedicine: Nanotechnology... · 0 citations