Oct 2026
CK2α O-GlcNAcylation affects its conformational stability and modulates its ability to phosphorylate RAD51.
Homologous recombination (HR) is a DNA repair pathway which contributes to maintaining genomic integrity. This pathway, which is often dysregulated in cancer treatments resistance, is dependent on RAD51 protein. RAD51 activity is regulated by post-translational modification, particularly its phosphorylation on threonin...
Nassim El-Kasmi, A. Defontaine, D. Marquis et al.
· Glycobiology · 0 citations