Author

Nontaphat Leerach

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Review Open access Sep 2026

Carbapenemase- and ESBL-producing Carbapenem-resistant Klebsiella pneumoniae in Thailand: A Systematic Review and Meta-analysis

Klebsiella pneumoniae is one of the major pathogens associated with multidrug resistance. This study aims to estimate the prevalence and characterize the molecular epidemiology of carbapenem-resistant K. pneumoniae in Thailand. We conducted a comprehensive search of PubMed, Embase, Scopus, ScienceDirect, and a Thai Jou...

Nontaphat Leerach, Narak Pravitra, Sopicha Aungkawimongkol et al. · Journal of Pure and Applied... · 0 citations

Open access Sep 2026

Tryptophan triggers the production of anthranilamide and quinazolinone derivatives in Streptomyces sp. PC4-3

Streptomycetes are a valuable source of bioactive compounds, yet their biosynthetic diversity is often limited in laboratory conditions. The one strain-many compounds (OSMAC) strategy has been used to trigger the production of diverse microbial metabolites. In the present work, we observed an increased production of an...

Tam Pooprasert, M. Feliciano, Sanya Sureram et al. · RSC Advances · 0 citations

Aug 2026

Papaverine ameliorates psoriasis-like skin inflammation by regulating immune cell differentiation and RAGE-S100A7 axis in an imiquimod-induced murine model.

Psoriasis is a chronic, immune-mediated inflammatory skin disease affecting at least 2% of the global population. Papaverine, an alkaloid with known anti-inflammatory, anti-cancer, and RAGE-antagonistic properties, has not been previously evaluated for anti-psoriatic activity. This study investigated the protective eff...

Nontaphat Leerach, Yupa Srithongchai, Sei-ichi Munesue et al. · Journal of Immunology · 0 citations